How To Use
- Using clean hands apply to clean skin AM and PM.
- Dab gently around the eye and massage into the skin.
- Allow to fully absorb 1-2 minutes
NOTE: Avoid getting the product into the eye.
Discover the ultimate eye cream developed by Dr. Nathan S. Bryan. Enhance firmness and hydration with this revolutionary formula. Upgrade your skincare routine now.
Maximum of 2 per order.
$59.98
In stock
NOTE: Avoid getting the product into the eye.
| Weight | .3 oz |
|---|---|
| Dimensions | 2 × 2 × 2 in |
“Loss of nitric oxide production is recognized as the earliest event in the onset and progression of most, if not all, chronic diseases, including the number one killer of men and women worldwide—cardiovascular disease.” —Dr. Nathan S. Bryan
Introducing N1o1 Nitric Oxide Boosting Age-Defiance Eye Cream, a trailblazing skincare solution crafted by Dr. Nathan S. Bryan. This eye cream utilizes the Nobel Prize-winning discovery of Nitric Oxide – hailed as the ‘anti-aging molecule’ – to rejuvenate the skin around your eyes, tackling the root cause of aging skin.
N1o1 Age-Defiance Eye Cream works at a cellular level, aiding the production of Nitric Oxide in your skin cells. This molecule plays a critical role in maintaining cellular health, ensuring moisture retention, nutrient absorption, and optimal function of collagen-building components. As we age, Nitric Oxide production decreases, leading to visible signs of aging. N1o1 skincare helps to restore this essential molecule, revitalizing your skin from within.
Moreover, our eye cream incorporates complex peptides and Hyaluronic Acid, both vital components in promoting firm, hydrated, youthful skin. Alongside Nitric Oxide, these ingredients work in synergy to dramatically reduce wrinkles, crow’s feet, dark circles, and fine lines.
Our Age-Defiance Face Cream works deep within your skin at a cellular level to help diminish signs of aging. It combines three remarkable anti-aging ingredients to specifically target problem areas: Nitric Oxide for promoting overall skin health and circulation to the skin; complex peptides for rejuvenating skin, and Epidermal Growth Factor (EGF) to stimulate collagen and elastin production.
Introducing AMAZING INGREDIENTS with the N1o1 Age-Defying Gel Cleanser that joins natural cleansers with natural botanical ingredients. It works wonderfully with N1o1 nitric oxide-activated anti-aging serum, face cream, and eye cream. The BENEFITS are immense:
Statements made have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
For the utmost protection against environmental stressors, our eye cream also features Ceramides, lipid molecules that form a protective skin barrier and assist in retaining moisture.
Experience the blend of nature and groundbreaking science with N101 Nitric Oxide Boosting Age-Defiance Eye Cream. Rediscover your skin’s youthful radiance and firmness and enjoy the confidence it brings.
Statements made have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
“Loss of nitric oxide production is recognized as the earliest event in the onset and progression of most, if not all, chronic diseases, including the number one killer of men and women worldwide—cardiovascular disease.” —Dr. Nathan S. Bryan
Clean ingredients
Cruelty-free
Vegan
Gluten-free
Low Sugar
Non-GMO
A nourishing oil rich in vitamins and fatty acids, used to moisturize and protect the skin.
A natural ingredient known for its hydrating and anti-aging properties, often used to retain moisture, improve skin elasticity, and reduce the appearance of fine lines and wrinkles.
A soothing and hydrating ingredient known for its cooling properties, used to refresh and calm the skin
An antioxidant-rich ingredient derived from green tea leaves, known for its soothing, anti-inflammatory, and anti-aging properties.
A versatile oil known for its moisturizing and antibacterial properties, used to hydrate and protect skin and hair.
Water, Cetearyl Alcohol, Glyceryl Stearate SE, Squalane, Dimethicone, Garcinia Indica Seed Butter, Ceteareth-20, Glycerin, Sodium Nitrite, Magnesium Aluminum Silicate, Sodium PCA, Palmitoyl Tripeptide-5, Propanediol, Polyacrylamide, Sodium Hyaluronate, Tremella Fuciformis (Mushroom) Extract, Palmitoyl Tripeptide-1, Dicaprylyl Ether, N-Hydroxysuccinimide, Cetyl Alcohol, Palmitoyl Tetrapeptide-7, Cetyl Esters, Dunaliella Salina Extract, C13-14 Isoparaffin, Biosaccharide Gum-1, Ceteareth-25, Steareth-20, Laureth-7, Behenic Acid, Phenoxyethanol, Cholesterol, Ceramide NP, Ceramide NS, Ceramide EOS, Ceramide EOP, Ceramide AP, Chrysin, Caprooyl Phytosphingosine, Caprooyl Sphingosine, Caprylyl Glycol, Panthenol, Lecithin, Titanium Dioxide
MEET THE FOUNDER
Dr. Nathan S. Bryan is an international leader in molecular medicine and nitric oxide biochemistry. Dr. Bryan’s discoveries have led to product and technology innovations that have improved patient care worldwide.
With over 20 years of research in cardiovascular health and molecular medicine, Dr. Bryan is one of the world’s foremost experts on Nitric Oxide’s role in human health.
His discoveries have shaped the field of Nitric Oxide therapy, leading to cutting-edge solutions like the N1o1 Nitric Oxide Lozenges you’re about to experience.
Dr. Bryan is dedicated to helping people unlock their body’s full potential through the power of Nitric Oxide—so they can live longer, healthier, and more vibrant lives.
[1] The Utilization of a Topical Nitric Oxide Generating Serum in the Aging Skin Population: A Pilot Study
Annals of Plastic & Reconstructive Surgery
Greg Chernoff* MD, FRCS(C)
Chernoff Plastic Surgery, Indianapolis, Indiana, Santa Rosa, California, US
Download the PDF
[2] The Utilization of a Nitric Oxide Generating Serum in the Treatment of Active Acne and Acne Scarred Patients
International Journal of Pharmaceutica Analytica Acta
Greg Chernoff
Department of Otolaryngology, Head and Neck Surgery, St. Vincent Hospital, Indianapolis, Indiana, United States
Download the PDF
[3] The Utilization of a Nitric Oxide Generating Serum for Improving Vascularity in Wound Healing
Science Repository
Greg Chernoff
Ascension St. Vincent Hospital, USA
Download the PDF
[4] The Utilization of a Topical Nitric Oxide Generating Serum in Aesthetic Medicine
Gavin Publishers
Gregory Chernoff BSc, MD, FRCS(C)
Private Practice, Chernoff Cosmetic Surgeons, Ascension St. Vincent Hospital, Indianapolis IN, USA
Download the PDF
[5] A Novel Combination Therapy in Aesthetic and Reconstructive Surgery: Sea Salt Exfoliation, Cavitating Ultrasound, and High Intensity Multiwavelength LED Treatment: (SaltFacial)
Sciforschen Journal of Clinical and Cosmetic Dermatology
Greg Chernoff, BSc, MD, FRCSC*
Department of Otolaryngology, Head and Neck Surgery, St. Vincent Hospital, Indianapolis, Indiana, United States
Download the PDF
AS SEEN IN
Terry M –
I’ve been using the N1 o1 serum for about 6 months and super happy with the results.
I was looking forward to trying the N1 o1 age-defiance eye cream to help with the dark area and fine lines around my eyes,
First, the packaging is beautiful. The eye cream is rich, smooth, reduced the dark area, and small lines around my eyes.
Martin W –
I like the texture, smell is very neutral, which i like, and it is filled completely to the top so be careful when taking off the lid, be ready to apply some. I have tried other N1O1 products and this is a great compliment and worth the price. after applying i could feel a slight tingling sensation, but seems to be working great to hydrate the area around my eyes. I am grateful there is a N1O1 store on amazon.
Tina L. –
I actually just receive my jar about 10 day ago because I live in Taiwan and I have to have it sent to my relatives in the US and her brother brought it to Taiwan for me , so only used for one week really can’t tell a whole lot but I did notice my dark spot gotten a bit lighter and under eye bag has some improvement I believe after finishing one jar I should have much noticeable change , this is the only kind of cream with cN1O1 which has done wonderful job to our body , check it out !
Karen Schwenke –
I saw almost immediate results, fine lines disappearing, dark circles gone. I will definitively purchase again.
CJo –
I love this eye cream. I am getting ready to start my 2nd jar. I have tried many eye creams and I think I found the one I will be staying with as I really love it. I use it every morning and night. Not greasy. I highly recommend you try it. You won’t be disappointed.
Swil75 –
I will admit I was a skeptic at first but figured I’d take the chance. So it’s only been a couple weeks but have already seen a difference. While it’s not drastic yet in the first couple weeks, I can definitely tell the lines have faded and under the eyes looks firmer. Excited to see what another couple weeks does! It is expensive for a small jar but in my opinion, worth the price for something that actually works. I will be re-ordering when it’s time!
Jeff Gonzales –
I am a huge fan of their serum and hoped or, more likely, assumed that the eye cream would work just as well and just as quickly. With the serum, it was only a matter of a few days before I started to notice some pretty fantastic results. A few months later, the lines on my forehead (my primary focus) are far less noticeable. 1 of my 4 lines is almost gone and another one is barely hanging on – out of spite, I’m sure. As far as the other 2, well, they are still there, but much less prominent. I admit, I’ve become a little obsessed, but couldn’t be happier with the results so far.
On to the Eye Cream. I kinda love this stuff. It’s creamy and rich and easy to use. I’ve been using it for about 3 to 4 weeks. I have noticed some subtle changes under my eyes. Not as dramatic as using the serum on my forehead, but I like what I see and I’m not giving up now.
I am definitely a fan.
Ari –
I’ve struggled with dark circles and fine lines for years, but the Age-Defiance Eye Cream has been a game-changer. Its lightweight texture absorbs quickly without feeling heavy, making it perfect for daily use. Within just a few weeks, the area under my eyes looked noticeably brighter, and the fine lines around them started to fade. It’s amazing to finally find something that truly works—I’m beyond thrilled!
Anna G. –
The Age-Defiance Eye Cream is exactly what my skin needed! The peptides in the formula really make a difference—my under-eye area feels incredibly hydrated and looks visibly firmer. Within days, I noticed a subtle lift that made my eyes look brighter and more awake. I couldn’t be happier with how refreshed and youthful my skin feels. Dr. Bryan makes the best products!
Layla –
I’m amazed at how quickly the Age-Defiance Eye Cream worked for me! My under-eye puffiness was always the first thing people noticed, but within just a few days of using this cream, the swelling reduced dramatically. It’s so gentle on my skin, and the overall texture of my eye area has improved—it’s so much smoother now. It’s a little jar of magic, and I’m so happy this is available to subscription so I don’t have to run into a fear of running out!
Nancy –
My eyes have never looked this refreshed! The Age-Defiance Eye Cream has an incredibly lightweight feel, so it’s perfect for wearing under makeup. Within a couple of weeks, my crow’s feet softened dramatically, and the area around my eyes now looks so much brighter. My tired eyes are finally rejuvenated, and I can’t imagine my routine without this cream—highly recommend. Five stars!!
Christopher Lopez –
I never paid much attention to skincare until my wife pointed out the dark circles under my eyes were making me look exhausted all the time. As a 38-year-old who works long hours in finance, I figured it came with the territory. But after using the Age-Defiance Eye Cream for about a month, the difference is really noticeable. The dark circles have lightened significantly, and those fine lines at the corners of my eyes aren’t as prominent. What I appreciate most is how lightweight it feels—no greasy residue or weird smell. It’s become part of my morning routine, and honestly, I look more refreshed and alert. Even my colleagues have commented that I seem more rested lately.
stephanie lang –
As a busy mom who’s always on the go, I started noticing the skin around my eyes looking tired and dull. Between sleepless nights and the stress of daily life, the fine lines and puffiness were getting worse. A friend recommended the Age-Defiance Eye Cream, and honestly, I wasn’t sure it would make a difference. But after using it twice a day for about six weeks, I’m amazed. The skin around my eyes looks smoother and more hydrated, and the puffiness has noticeably reduced. It’s lightweight, absorbs quickly, and fits perfectly into my skincare routine. I feel more refreshed and confident, even without makeup. This has definitely become a go-to product for me!
Regina luis –
I’m a nurse so I’m constantly on my feet and working long shifts, I started noticing the effects of stress and sleepless nights on my eyes. Fine lines, puffiness, and a tired, dull look became all too common. I’ve always been fan of Dr. Bryan’s work so I finally decided to give the n1o1 eye cream a try, I didn’t expect much—but I decided to give it a shot. After using it everyday for a month, I’m blown away by the difference. The puffiness has gone down, my fine lines look softer, and my skin feels smoother and more hydrated. Now, even after night shifts, I look more awake.
Suzie K. –
Best eye cream on the market. Expensive for the size but with consistent use, i feel like this really makes a difference for my under-eye bags